Dr. Shankara Paneesha discussed the evolving treatment landscape for relapsed CLL, focusing on BTK resistance, new treatment options including cellular therapy, and the importance of patient-specific factors in treatment decisions.
Dr. Romain Guieze presents a case study on managing chronic lymphocytic leukemia (CLL) with a focus on treatment options, resistance mechanisms, and genetic testing for a 72-year-old patient with a history of uncontrolled hypertension and multiple relapses.
Navigating CLL Treatment: Approved Therapies and Overcoming Resistance Read More »
The research discusses the role of BCL-2 overexpression in chronic lymphocytic leukemia (CLL) and the efficacy of the BCL-2 inhibitor venetoclax in treating the disease. It highlights the challenges of resistance mechanisms that arise during treatment, such as BCL-2 mutations and metabolic changes, and emphasizes the potential of combination therapies to improve patient outcomes and achieve durable remissions.
BCL2i-Based Therapies and Emerging Resistance in Chronic Lymphocytic Leukemia Read More »
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